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Allison Shu-chi Yeh (葉書綺)


Allison Yeh Ph.D. Candidate, Biomedical Engineering, McMaster University
B.Sc. Physical Therapy, 2007, CSMU, Taiwan R.O.C.

Contact Information

Office: ETB/303
Email: yehsc@mcmaster.ca
Lab Phone: 905-963-3777

Mailing Address
ETB 405 School of Biomedical Engineering
McMaster University
1280 Main Street West
Hamilton, ON L8S 4L7, Canada


Thesis projects/ Research Interests

Allison Yeh’s current research involves the project of PDT dosimetry in cancer research and integrated detection and ablation of Barrett's esophageal cell lines using the PDT photosensitizer,5-aminolevulinic acid (5-ALA). The research projects involve the use of fluorescence lifetime imaging microscopy, confocal and multiphoton microscopy, and image processing. She is also interested in other microscopic applications and computational design preferably with a focus on the applications of molecular probes, in vivo imaging, and machine learning.

Research projects

Allison's main academic interests include:

  • Characterization of the fluorescence lifetimes of PDT photosensitizers
  • Real-Time Dosimetry of PDT
  • 5-ALA based detection and laser ablation of Barrett's esophagus


Awards


Publications

  • Shu-Chi Allison Yeh, Kevin Diamond, Michael Patterson, Zhaojun Nie, Joseph Hayward, Qiyin Fang, “Monitoring Photosensitizer Uptake Using Two Photon Fluorescence Lifetime Imaging Microscopy,” Theranostics; 2(9):817-826, 2012 (Open Access).
  • Regina Won Kay Leung, Shu-Chi Allison Yeh, and Qiyin Fang, “Effects of incomplete decay in fluorescence lifetime estimation,” Biomedical Optics Express 2(9):2517–2531, 2011. (PDF)


Conference Proceedings

  • Pouya Rezai, Shu-Chi (Allison) Yeh, Sangeena Salam, Qiyin Fang, Bhagwati P Gupta, Ponnambalam R Selvaganapathy. Co-relation of cellular and behavioral responses of caenorhabditis elegans to pulse DC electric fields. W.2.59 (1630), MicroTAS (2012).


Conference Oral Presentations

  • Shu-chi Allison Yeh, Kevin Diamond, Michael Patterson, Zhaojun Nie, Joseph Hayward, Qiyin Fang, “Monitoring Photosensitizer Uptake Using Two Photon Fluorescence Lifetime Imaging Microscopy” SPIE Photonics West Bios (Abstract #8568-37, 2013)
  • Shu-chi Allison Yeh, Tony Collins, Kevin Diamond, Regina Leung, & Qiyin Fang, “Using Fluorescence Lifetime Imaging Microscopy to Monitor Photofrin Uptake, Redistribution, and Intracellular Microenvironment” 217th ECS Meeting Section: E3 - Integrated Optoelectronics 5


Conference Poster Presentations

  • Shu-Chi A. Yeh, Regina W. K. Leung, Qiyin Fang, “Effects of incomplete decay in fluorescence lifetime estimation.
    • Paper NIH100-106, 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside, September 15 (2011)
  • Shu-chi Yeh, Tony J. Collins, Kevin Diamond, Qiyin Fang. “Photofrin Uptake Monitored by FLIM”
    • in Biomedical Optics (BIOMED)/ Digital Holography and Three-Dimensional Imaging (DH) on CD-ROM (The Optical Society, Washington, DC, 2010), presentation number ISBN: 978-1-55752-887-2

Schedule (September 2013- December 2013)

Time Monday Tuesday Wednesday Thursday Friday
8:30 - 9:30 CAS 708 CAS 708
9:30 - 10:30 CAS 708 CAS 708
10:30 - 11:30
11:30 - 12:30
12:30 - 13:30 Experiment Experiment
13:30 - 14:30 Experiment Experiment
14:30 - 15:30 Experiment Experiment
15:30 - 16:30 Experiment Experiment
16:30 - 17:30 Experiment Experiment
17:30 - 18:30 Experiment Experiment

**Experiment schedules are flexible (usually on Wednesdays and Fridays but will be based on the availability of specific instruments and samples)

Safety Training

Base CoursesAdditional Courses
CourseDateCourseDate
WHMIS 2008 Laser Safety 2009
Fire Safety 2008 Biosafety, BSL2 2009, 2010, 2011,2012, 2013
Asbestos Awareness 2008 WHIMIS Core 2009, 2011,2012, 2013
Ergonomics 2008 Fire Safety (HSC) 2009, 2011,2012, 2013
Slips/Trips/Falls 2008 Lab specific biosafety training 2012, McMaster Biophotonics Facility HSC 4H14/4H41
Electrical Safety 2012

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