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Alzheimer's Disease Powerpoint
Alzheimer's Disease
INTRODUCTION
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SIGNS & SYMPTOMS
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EPIDEMIOLOGY
Key Points:
- Worldwide, nearly 44 million people have Alzheimer’s or a related dementia.
- Only 1-in-4 people with Alzheimer’s disease have been diagnosed.
- Alzheimer’s and dementia is most common in Western Europe (North America is close behind).
- Alzheimer’s is least prevalent in Sub-Saharan Africa.
- Alzheimer’s and other dementias are the top cause for disabilities in later life. (Alzheimer’s Disease International, 2015)
The incidence of AD is approximately 5–8 for per thousand person, which represents half of new dementia cases each year are AD (Bermejo-Pareja et al, 2008). One of the primary risk factor for AD, where there is a correlation of the incidence rate of every five years after the age of 65, the risk of acquiring AD approximately doubles (Di Carlo et al, 2002). Furthermore, there is also higher incidence rates in women compared to men of developing AD particularly in the population older than 85 (Andersen et al, 1999). In the United States, Alzheimer prevalence was estimated to be 1.6% in 2000 both overall and in the 65–74 age group, with the rate increasing to 19% in the 75–84 group and to 42% in the greater than 84 group. (Hebert et al, 2003) Prevalence rates of AD is less in developed countries compared to developing countries (Ferri et al, 2006). AD accounts to 50-70% of all forms of dementia, making it the leading cause of this neurodegenerative disease (7). Furthermore, due to the rapid increase of dementia, individuals would also be at increased risk of AD. Another study estimated that in 2006, 0.40% of the world population were afflicted by AD, and that the prevalence rate would triple and the absolute number would quadruple by 2050. (Brookmeyer et al, 2007)
DIAGNOSIS
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PATHOPHYSIOLOGY
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CURRENT TREATMENTS
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FUTURE TREATMENTS
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