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group_5_presentation_2_-_alzheimers [2018/11/04 18:16] chuj19 [Aducanumab Targeting Beta-amyloid Protein] |
group_5_presentation_2_-_alzheimers [2018/11/04 18:27] (current) chuj19 [Alzheimer's Disease] |
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| ======= Alzheimer's Disease ======= | ======= Alzheimer's Disease ======= | ||
| + | {{ :alzheimer-disease.jpg?direct&600 |}} | ||
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| An individual who has AD requires attention from health professionals as patients who have severe AD may experience more behavioural and psychological symptoms. For example, monitoring can include assessing the function, cognition, and nutritional status from frequent visits to family physicians (Herrmann and Gauthier, 2008). Patients with AD may have increased agitation, aggression, and motor restlessness. It is important that caregivers to recognize further distress and provide quality life for the patient, maintain optimal function, and provide maximum comfort (Herrmann and Gauthier, 2008.) Furthermore, evaluating treatment and providing continuous and guidance to the patient as well as the caregiver is extremely important. (Waldemar et al., 2007). Evaluating medication effects and treatments requires both the cooperation from the caregiver as well as physician (Waldemar et al., 2007). | An individual who has AD requires attention from health professionals as patients who have severe AD may experience more behavioural and psychological symptoms. For example, monitoring can include assessing the function, cognition, and nutritional status from frequent visits to family physicians (Herrmann and Gauthier, 2008). Patients with AD may have increased agitation, aggression, and motor restlessness. It is important that caregivers to recognize further distress and provide quality life for the patient, maintain optimal function, and provide maximum comfort (Herrmann and Gauthier, 2008.) Furthermore, evaluating treatment and providing continuous and guidance to the patient as well as the caregiver is extremely important. (Waldemar et al., 2007). Evaluating medication effects and treatments requires both the cooperation from the caregiver as well as physician (Waldemar et al., 2007). | ||
| - | ====== Conclusion and Future Therapeutics ===== | + | ====== Future Therapeutics ===== |
| ==== Aducanumab Targeting Beta-amyloid Protein ==== | ==== Aducanumab Targeting Beta-amyloid Protein ==== | ||
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| {{ :375px-pdb_1i8h_ebi.jpg?direct&300 |}} Figure 6: Picture of the tau protein structure. | {{ :375px-pdb_1i8h_ebi.jpg?direct&300 |}} Figure 6: Picture of the tau protein structure. | ||
| + | ====== Conclusion ====== | ||
| + | Although there currently is not a definite cure for Alzheimer's disease, current research such as Aducanumab and AADvac1 shows promising progression with research. Furthermore, other research focusing on the inflammation of the brain with the disease is also being researched and will hopefully pass the trials so patients are able to use the drug. There are also many preventive ways described within the 4 pillars of Alzheimer's Prevention and the management of the patient is just as important. | ||
| ====== References ====== | ====== References ====== | ||
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| Alzheimer's Disease. (n.d.). Retrieved from https://www.saintlukeskc.org/condition/alzheimers-disease | Alzheimer's Disease. (n.d.). Retrieved from https://www.saintlukeskc.org/condition/alzheimers-disease | ||
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| + | Alzheimer's Disease: Symptoms and Care | Emed Multi Specialty Group. (2018, May 07). Retrieved from https://emedmultispecialtygroup.com/2018/03/20/alzheimers-disease-symptoms-care/ | ||
| Alzheimer's Prevention. (2018). Alzheimer's Prevention through Diet and Supplements, Stress Management, Exercise, and Spiritual Fitness. [online] Available at: http://alzheimersprevention.org/4-pillars-of-prevention/ [Accessed 30 Oct. 2018]. | Alzheimer's Prevention. (2018). Alzheimer's Prevention through Diet and Supplements, Stress Management, Exercise, and Spiritual Fitness. [online] Available at: http://alzheimersprevention.org/4-pillars-of-prevention/ [Accessed 30 Oct. 2018]. | ||
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| Wisniewski, T., Castano, E. M., Golabek, A., Vogel, T., & Frangione, B. (1994). Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. The American journal of pathology, 145(5), 1030. | Wisniewski, T., Castano, E. M., Golabek, A., Vogel, T., & Frangione, B. (1994). Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. The American journal of pathology, 145(5), 1030. | ||
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