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group_4_presentation_1_-_synthetic_antibody_mimics [2016/01/29 19:32] venkaa2 |
group_4_presentation_1_-_synthetic_antibody_mimics [2018/01/25 15:18] (current) |
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| ====== Fighting Against Disease ====== | ====== Fighting Against Disease ====== | ||
| - | ==== A Body's Natural Defenses ==== | + | ==== The Body's Natural Defenses ==== |
| The human body is generally quite effective in targeting and eliminating disease-causing agents (e.g. viruses & bacteria). It accomplishes this via its immune system which has two branches: Innate immune system and Adaptive immune system. The innate immune system is quite general and fights anything foreign in the body immediately. Examples of the innate immune system include physical barriers such as epithelial layers as well as chemical barriers such as mucosal layers and innate infection fighting cells such as macrophages (Parham, 2014). The adaptive immune system is more specific and takes some time to activate; however, it is responsible for clearing those pathogens that are able to evade the innate immune system and infect various cells within the human body. The adaptive immune system is heavily reliant on antibodies. These antibodies are produced by Plasma cells which are B-cells primed by dendritic cells upon contact of infectious pathogen in lymphatic system of the human body (Parham, 2014). | The human body is generally quite effective in targeting and eliminating disease-causing agents (e.g. viruses & bacteria). It accomplishes this via its immune system which has two branches: Innate immune system and Adaptive immune system. The innate immune system is quite general and fights anything foreign in the body immediately. Examples of the innate immune system include physical barriers such as epithelial layers as well as chemical barriers such as mucosal layers and innate infection fighting cells such as macrophages (Parham, 2014). The adaptive immune system is more specific and takes some time to activate; however, it is responsible for clearing those pathogens that are able to evade the innate immune system and infect various cells within the human body. The adaptive immune system is heavily reliant on antibodies. These antibodies are produced by Plasma cells which are B-cells primed by dendritic cells upon contact of infectious pathogen in lymphatic system of the human body (Parham, 2014). | ||
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| {{:crystallized_structure_of_fcgammar1.png|}} | {{:crystallized_structure_of_fcgammar1.png|}} | ||
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| **Figure 5**: Shows the crystallized structure of FcγRI (McEnaney et al., 2014). | **Figure 5**: Shows the crystallized structure of FcγRI (McEnaney et al., 2014). | ||
