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group_4_presentation_1_-_migraines [2018/02/02 20:01] chowds6 |
group_4_presentation_1_-_migraines [2018/02/15 15:34] (current) pablahk2 [Presentation] |
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| ====== Conclusion ====== | ====== Conclusion ====== | ||
| - | Overall, migraines are a primary headache disorder, characterized by recurrent throbbing, heightened severity, length, localization of pain to one side of the head, amongst other symptoms (vomiting, nausea, sensitivity to light and smell). These symptoms are observed a high prevalence rate globally by age, with females experiencing more migraines than males overall. In addition, although the causes and triggers to migraine onset remains unclear, multiple studies have observed patients being most susceptible to stress, certain foods and drink, as well as other associated environmental and biological factors (light, weather, menstruation, hunger, etc.). What can be understood currently about this phenomenon is how migraines are a neurovascular disorders, mainly due to cortical spreading and the activation of trigeminovascular system seen in the brain and central nervous system. Beyond this scope however, the rest is relatively unclear, specifically concerning the mechanisms at play. It has been theorized that migraines are associated to a single nucleotide polymorphism on chromosome 8 or a frameshift mutation in the KCNK18 gene. With this current understanding about migraines, diagnosis can be completed quickly and treatment can be implemented at any migraine stage via acute or proactive methods. Yet, despite the efforts in providing a myriad of pharmaceutical and alternative treatments to the public, more has to be done to further learn how migraines occur and how to effectively lessen their severity for individuals. | + | Overall, migraines are a primary headache disorder, characterized by recurrent throbbing, heightened severity, length, localization of pain to one side of the head, amongst other symptoms (vomiting, nausea, sensitivity to light and smell). These symptoms are observed at a high prevalence rate globally by age, with females experiencing more migraines than males overall. In addition, although the causes and triggers to migraine onset remains unclear, multiple studies have observed patients being most susceptible to stress, certain foods and drink, as well as other associated environmental and biological factors (light, weather, menstruation, hunger, etc.). What can be understood currently about this phenomenon is how migraines are a neurovascular disorders, mainly due to cortical spreading and the activation of trigeminovascular system seen in the brain and central nervous system. Beyond this scope however, the rest is relatively unclear, specifically concerning the mechanisms at play. It has been theorized that migraines are associated to a single nucleotide polymorphism on chromosome 8 or a frameshift mutation in the KCNK18 gene. With this current understanding about migraines, diagnosis can be completed quickly and treatment can be implemented at any migraine stage via acute or proactive methods. Yet, despite the efforts in providing a myriad of pharmaceutical and alternative treatments to the public, more has to be done to further learn how migraines occur and how to effectively lessen their severity for individuals. |
| ====== Presentation ===== | ====== Presentation ===== | ||
| - | Click [[https://docs.google.com/presentation/d/1ibVISwfdNHMTD9H5oXmE6uUsJUpKaYechKKErD2faeM/edit?usp=sharing|here]] for a research seminar presentation on migraines. | + | Click {{:presentation_1_migraines.pdf|}} for a research seminar presentation on migraines. |
| **Copyright ©** Miguel Cardoso, Shara Chowdhury, Sabrina Musto, Harpreet Pabla, & Ojan Yarkhani | **Copyright ©** Miguel Cardoso, Shara Chowdhury, Sabrina Musto, Harpreet Pabla, & Ojan Yarkhani | ||
