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group_2_presentation_1_-_effects_of_the_cocaine_on_the_brain [2016/09/30 14:04]
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group_2_presentation_1_-_effects_of_the_cocaine_on_the_brain [2018/01/25 15:18] (current)
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 The risk for becoming dependant in the first two years of use is 5-6%, while becoming dependant within 10 years of first use increases to 15-16%. Studies show that the chances of becoming dependant on cocaine was lower when individuals snorted cocaine; higher when smoking, and much higher for injecting. ​ Women are 3.3 times more likely to become dependent when compared to men. Those who started at a younger age, 12-13, were four times more likely to become dependent when compared to those who started at ages 18-20. The peak age for dependence is at ages 23-25. [21] The risk for becoming dependant in the first two years of use is 5-6%, while becoming dependant within 10 years of first use increases to 15-16%. Studies show that the chances of becoming dependant on cocaine was lower when individuals snorted cocaine; higher when smoking, and much higher for injecting. ​ Women are 3.3 times more likely to become dependent when compared to men. Those who started at a younger age, 12-13, were four times more likely to become dependent when compared to those who started at ages 18-20. The peak age for dependence is at ages 23-25. [21]
  
-{{:meoww.jpg|}} +{{:figure_71_cocaine.jpg|}}
-//Figure 7: Graph showing dependance on Cocaine use relative to age group // +
-http://​www.nature.com/​npp/​journal/​v26/​n4/​full/​1395810a.html+
  
  
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   - Nicholls, J.G., Mar5n, A.R., Wallace, B.G. & Fuchs, P.A. (2001) From Neuron to Brain, 4th Ed.   - Nicholls, J.G., Mar5n, A.R., Wallace, B.G. & Fuchs, P.A. (2001) From Neuron to Brain, 4th Ed.
   - Breiter, Hans C., et al. "Acute effects of cocaine on human brain activity and emotion."​ Neuron 19.3 (1997): 591-611.   - Breiter, Hans C., et al. "Acute effects of cocaine on human brain activity and emotion."​ Neuron 19.3 (1997): 591-611.
 +  - Mackey, S., & Paulus, M. (2013, March). Are there volumetric brain differences associated with the use of cocaine and amphetamine-type stimulants? Neuroscience & Biobehavioral Reviews, 37(3), 300-316. doi:​10.1016/​j.neubiorev.2012.12.003
 +  - Dubuc, B. (n.d.). THE BRAIN FROM TOP TO BOTTOM. Retrieved September 21, 2016, from http://​thebrain.mcgill.ca/​flash/​i/​i_03/​i_03_cr/​i_03_cr_par/​i_03_cr_par.html
   - Robinson, T. E., Gorny, G., Mitton, E., & Kolb, B. (2001). Cocaine self‐administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens- ​ and neocortex. Synapse, 39(3), 257-266. doi:​10.1002/​1098 2396(20010301)39:​33.3.co;​2-t   - Robinson, T. E., Gorny, G., Mitton, E., & Kolb, B. (2001). Cocaine self‐administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens- ​ and neocortex. Synapse, 39(3), 257-266. doi:​10.1002/​1098 2396(20010301)39:​33.3.co;​2-t
-  - Dubuc, B. (n.d.). THE BRAIN FROM TOP TO BOTTOM. Retrieved September 21, 2016, from http://​thebrain.mcgill.ca/​flash/​i/​i_03/​i_03_cr/​i_03_cr_par/​i_03_cr_par.html 
   - Porter, J. N., Minhas, D., Lopresti, B. J., Price, J. C., & Bradberry, C. W. (2014). Altered cerebellar and prefrontal cortex function in rhesus monkeys that previously self- administered cocaine. Psychopharmacology,​ 231(21), 4211-4218. doi:​10.1007/​s00213-014-3560-   - Porter, J. N., Minhas, D., Lopresti, B. J., Price, J. C., & Bradberry, C. W. (2014). Altered cerebellar and prefrontal cortex function in rhesus monkeys that previously self- administered cocaine. Psychopharmacology,​ 231(21), 4211-4218. doi:​10.1007/​s00213-014-3560-
 +  - Paulin, M.G. (1993). ​ The Role of the Cerebellum in Motor Control and Perception. Brain Behav Evol, 41(1), 39-50 1993. http://​www.otago.ac.nz/​neurozoo/​documents/​Paulin%201993%20-%20role%20of%20the%20cerebellum.pdf
   - Bechara, A. (2000). Emotion, Decision Making and the Orbitofrontal Cortex. Cerebral Cortex, 10(3), 295-307. doi:​10.1093/​cercor/​10.3.295   - Bechara, A. (2000). Emotion, Decision Making and the Orbitofrontal Cortex. Cerebral Cortex, 10(3), 295-307. doi:​10.1093/​cercor/​10.3.295
   - Hester, R. (2004). Executive Dysfunction in Cocaine Addiction: ​ Evidence for Discordant Frontal, Cingulate, and Cerebellar Activity. Journal of Neuroscience,​ 24(49), 11017-11022. doi:​10.1523/​jneurosci.3321-04.2004   - Hester, R. (2004). Executive Dysfunction in Cocaine Addiction: ​ Evidence for Discordant Frontal, Cingulate, and Cerebellar Activity. Journal of Neuroscience,​ 24(49), 11017-11022. doi:​10.1523/​jneurosci.3321-04.2004
   - Lucantonio, F., Takahashi, Y. K., Hoffman, A. F., Chang, C., Bali-Chaudhary,​ S., Shaham, Y., Schoenbaum, G. (2014). Erratum: Orbitofrontal activation restores insight lost after cocaine use. Nature Neuroscience Nat Neurosci, 17(9), 1287-1287. doi:​10.1038/​nn0914-1287e   - Lucantonio, F., Takahashi, Y. K., Hoffman, A. F., Chang, C., Bali-Chaudhary,​ S., Shaham, Y., Schoenbaum, G. (2014). Erratum: Orbitofrontal activation restores insight lost after cocaine use. Nature Neuroscience Nat Neurosci, 17(9), 1287-1287. doi:​10.1038/​nn0914-1287e
-  - Bechara, A. (2000). Emotion, Decision Making and the Orbitofrontal Cortex. Cerebral Cortex, 10(3), 295-307. doi:​10.1093/​cercor/​10.3.295 
   - Behavioral health trends in the United States: Results from the 2014 National Survey on Drug Use and Health (HHS Publication No. SMA 15-4927, NSDUH Series H-50). Retrieved from http://​www.samhsa.gov/​ data/   - Behavioral health trends in the United States: Results from the 2014 National Survey on Drug Use and Health (HHS Publication No. SMA 15-4927, NSDUH Series H-50). Retrieved from http://​www.samhsa.gov/​ data/
   - What is the scope of cocaine use in the United States? (2016). Drugabuse.gov. Retrieved 23 September 2016, from https://​www.drugabuse.gov/​publications/​research-reports/​cocaine/​what-scope-cocaine-use-in-united-states   - What is the scope of cocaine use in the United States? (2016). Drugabuse.gov. Retrieved 23 September 2016, from https://​www.drugabuse.gov/​publications/​research-reports/​cocaine/​what-scope-cocaine-use-in-united-states
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