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| + | Presentation Link: https://docs.google.com/presentation/d/1JTOyofzyonkOJB61Z4LkGVThkePZB4uRO4ffWTzTRkY/edit#slide=id.gc6f90357f_0_0 | ||
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| ====== The Effects of Exercise on Cardiovascular Function ====== | ====== The Effects of Exercise on Cardiovascular Function ====== | ||
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| The cardiac electrical conduction system sets and maintains the rhythmic pumping action of the heart. The electrical impulses from the myocardium cause the heart to contract. The impulse begins at the sinoatrial (SA) node, which is found at the top of the right atrium. The electrical impulse form the SA node leads to the contraction of the atria, which signals the atrioventricular (AV) node. The impulse is then sent through the muscle fibres of the ventricles, cause the heart to contract. The cycle repeats (Cheng et al., 1999). | The cardiac electrical conduction system sets and maintains the rhythmic pumping action of the heart. The electrical impulses from the myocardium cause the heart to contract. The impulse begins at the sinoatrial (SA) node, which is found at the top of the right atrium. The electrical impulse form the SA node leads to the contraction of the atria, which signals the atrioventricular (AV) node. The impulse is then sent through the muscle fibres of the ventricles, cause the heart to contract. The cycle repeats (Cheng et al., 1999). | ||
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| ==Heart Rate Differences by Gender and Age== | ==Heart Rate Differences by Gender and Age== | ||
| Heart rate responds differently to exercise based on gender and age. Men’s heart rate tends to rise more dramatically toward peak levels during exercise and return to resting levels after exercise more quickly than women. Men’s maximum heart rate is expected to be 200 minus 93% of their age. Women’s maximum heart rate is expected to be 200 minus 67% of their age. Furthermore, peak heart rate declines with age but the decline is more rapid in men (“The Heart Responds Differently to Exercise in Men vs. Women,” n.d.). | Heart rate responds differently to exercise based on gender and age. Men’s heart rate tends to rise more dramatically toward peak levels during exercise and return to resting levels after exercise more quickly than women. Men’s maximum heart rate is expected to be 200 minus 93% of their age. Women’s maximum heart rate is expected to be 200 minus 67% of their age. Furthermore, peak heart rate declines with age but the decline is more rapid in men (“The Heart Responds Differently to Exercise in Men vs. Women,” n.d.). | ||
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| + | ====== Effects on Blood Pressure ====== | ||
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| + | Blood pressure has been deemed as a risk factor for cardiovascular disease for several decades. However, aerobic exercise has been shown to mitigate this risk. In fact, aerobic exercise has been shown to decrease ambulatory blood pressure in individuals (Brownley, West, Hinderliter, & Light, 1996). This can be seen in the figure above. In the graph, blood pressure at work (usually higher due to a variety of stressors at the workplace) shows greater reduction in blood pressure than at home. This is because the work segment of the day is usually shortly after morning exercise whereas the home segment is usually several hours later. In the study, exercise was shown to decrease blood pressure 2-5 hours post exercise after which the effects start to diminish (Brownley et al., 1996). | ||
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| + | Furthermore, several studies have found varying levels of reduction in blood pressure. One particular study has shown that exercise can reduce blood pressure by 4 mm Hg (Blumenthal et al., 2000). This is depicted in the above figure. The bars on the left (exercise + diet) show the greatest reduction in blood pressure however, the bars in the middle show that exercise alone is also sufficient in reducing blood pressure. | ||
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| + | ====== Effects on Cardiac Output ====== | ||
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| + | The heart, like any muscle, can grow with exercise since it is required to perform at a high level during such activity. The growth of cardiac muscle and simultaneous thickening of ventricular walls has been shown to lead to increased overall perfusion (Burton, Stokes, & Hall, 2004). Additionally, blood returns to the heart using skeletal muscles (which perform better with exercise). Therefore, exercise allows for greater smoothness of the venous blood flow which allows more blood to return to the heart (Lee & Oh, 2016). This allows the heart to pump more blood with each contraction. Higher levels of cardiac output also increase exercise capacity since trained athletes can show up to 40L greater cardiac output than untrained individuals (Lee & Oh, 2016). Lastly, with exercise the heart is able to undergo angiogenesis/coronary collateralization (Gertz et al., 2006). This essentially means that additional vessels are grown and perfuse the heart much better which allows for better cardiac function. Specifically, this increases overall perfusion as well as cerebral blood flow which has been shown to improve long-term stroke outcomes (Gertz et al., 2006). | ||
| ====== Epicardial Fat ====== | ====== Epicardial Fat ====== | ||
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| Epicardial fat is a build up of triglycerides usually located between the myocardium, also known as the muscular tissue of the heart, and the pericardium, which is the sac that encloses the heart (Bertaso, Bertol, Duncan & Foppa, 2013). This area does not typically contain large amounts of triglycerides. Consequently, when there is a large build up of epicardial fat it may lead to issues such as high blood pressure, coronary atherosclerosis, obesity and diabetes mellitus, among other problems (Bertaso et al., 2013). Thus, epicardial fat is often used as a key marker for cardiovascular risk. In addition, there are a variety of factors that affect the amount of epicardial fat such as age, gender, and ethnicity (Bertaso et al., 2013). | Epicardial fat is a build up of triglycerides usually located between the myocardium, also known as the muscular tissue of the heart, and the pericardium, which is the sac that encloses the heart (Bertaso, Bertol, Duncan & Foppa, 2013). This area does not typically contain large amounts of triglycerides. Consequently, when there is a large build up of epicardial fat it may lead to issues such as high blood pressure, coronary atherosclerosis, obesity and diabetes mellitus, among other problems (Bertaso et al., 2013). Thus, epicardial fat is often used as a key marker for cardiovascular risk. In addition, there are a variety of factors that affect the amount of epicardial fat such as age, gender, and ethnicity (Bertaso et al., 2013). | ||
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| == Epicardial Fat & Atherosclerosis == | == Epicardial Fat & Atherosclerosis == | ||
| Epicardial fat may instigate many different diseases cardiovascular diseases, such as atherosclerosis.This is a disease in which plaque deposits in the arteries. In the long-term these plaque deposits harden, and actually narrow the arteries (“Atherosclerosis”, 2018). This narrowing is quite dangerous because it makes it difficult for oxygen-rich blood, which moves through arteries, to reach vital organs in the human body. The epicardial fat and coronary vessels are quite close to each other (Gleeson et al., 2011). This allows for fatty acids and adipokines to seamlessly move between adipose tissue and the arteries. In addition, this build-up may lead to other issues such as lipotoxicity, which can lead to cell death (Golbidi & Laher, 2012). | Epicardial fat may instigate many different diseases cardiovascular diseases, such as atherosclerosis.This is a disease in which plaque deposits in the arteries. In the long-term these plaque deposits harden, and actually narrow the arteries (“Atherosclerosis”, 2018). This narrowing is quite dangerous because it makes it difficult for oxygen-rich blood, which moves through arteries, to reach vital organs in the human body. The epicardial fat and coronary vessels are quite close to each other (Gleeson et al., 2011). This allows for fatty acids and adipokines to seamlessly move between adipose tissue and the arteries. In addition, this build-up may lead to other issues such as lipotoxicity, which can lead to cell death (Golbidi & Laher, 2012). | ||
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| There are several exercises that are beneficial to maintaining healthy cardiovascular function. There are four types of exercises that are recommended for people who have suffered a stroke before (Gordon et al., 2004). These include any aerobic, strength, flexibility, and neuromuscular exercise. The key is to vary the intensity, frequency, and duration of each exercise depending on your age and health conditions. For stroke survivors, the intensity, frequency, and duration for each of the four types of exercises are summarized in the table below (Gordon et al., 2004). | There are several exercises that are beneficial to maintaining healthy cardiovascular function. There are four types of exercises that are recommended for people who have suffered a stroke before (Gordon et al., 2004). These include any aerobic, strength, flexibility, and neuromuscular exercise. The key is to vary the intensity, frequency, and duration of each exercise depending on your age and health conditions. For stroke survivors, the intensity, frequency, and duration for each of the four types of exercises are summarized in the table below (Gordon et al., 2004). | ||
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| - | The most recommended exercise was aerobic because that has the largest impact on the heart. Researchers stated that the treadmill is an excellent machine to use because stroke survivors can increase the incline of the treadmill while maintaining the same speed (Gordon et al., 2004). This function on the treadmill is very beneficial because some stroke survivors have difficult climbing stairs. By using the treadmill, the stroke survivors will gradually build up the strength to be able to climb stairs again. | + | The most recommended exercise was aerobic because that has the largest impact on the heart. Researchers stated that the treadmill is an excellent machine to use because stroke survivors can increase the incline of the treadmill while maintaining the same speed (Gordon et al., 2004). This function on the treadmill is very beneficial because some stroke survivors have difficult climbing stairs. By using the treadmill, the stroke survivors will gradually build up the strength to be able to climb stairs again. The other exercises are recommended for people who are able to do it in addition to aerobic exercises. These exercises can help speed up the rehabilitation process by helping stroke survivors to strengthen muscles and maintain proper balance and posture. |
| ====== Electrocardiogram (ECG) ====== | ====== Electrocardiogram (ECG) ====== | ||
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| An ECG is a quick non-invasive test that is conducted to detect a patient’s risk of experiencing a heart problem (Adam Szulewski, n.d.). It is a common test that is given to many people that complain of chest pains or burning sensations around the area of the heart. Although it is a very simple and easy test to perform, it is very difficult to interpret the results and requires a lot of practice. One type of information that can be obtained through an ECG is a person’s heart rate (Adam Szulewiski, n.d.). The way to calculate the heart rate is to first locate two QRS complexes on the ECG. The QRS complex is the movement of electrical impulses through the lower chambers of the heart (Healthwise Staff, 2012). | An ECG is a quick non-invasive test that is conducted to detect a patient’s risk of experiencing a heart problem (Adam Szulewski, n.d.). It is a common test that is given to many people that complain of chest pains or burning sensations around the area of the heart. Although it is a very simple and easy test to perform, it is very difficult to interpret the results and requires a lot of practice. One type of information that can be obtained through an ECG is a person’s heart rate (Adam Szulewiski, n.d.). The way to calculate the heart rate is to first locate two QRS complexes on the ECG. The QRS complex is the movement of electrical impulses through the lower chambers of the heart (Healthwise Staff, 2012). | ||
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| The QRS complex in the ECG shown above is indicated by the two red arrows labelled 1 and 2. Now the distance between these two peaks is about 2 full box lengths. To obtain the heart rate, you simply divide 300 by the distance between the two peaks which is two. So, for this ECG the heart rate is approximately 150bpm. | The QRS complex in the ECG shown above is indicated by the two red arrows labelled 1 and 2. Now the distance between these two peaks is about 2 full box lengths. To obtain the heart rate, you simply divide 300 by the distance between the two peaks which is two. So, for this ECG the heart rate is approximately 150bpm. | ||
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| The two ECG images shown above indicate the differences between a resting heart rate and heart rate during exercise (Adam Szulewski, n.d.). The image on the left is what a normal ECG would look like for a healthy person at rest. You can see that the distance between two QRS complexes (peaks) is about 3.4 box lengths. So, the heart rate for this person would be approximately 88bpm. The actual number calculated by the author for this ECG is 82bpm (Adam Szulewski, n.d.). So, this quick method of measuring heart rate is very useful as the estimate is relatively close to the actual calculated value. On the right is an image of what an ECG looks like for tachycardia which means fast heart. This is what a person’s ECG would look like when they are exercising. The distance between the two QRS complexes (peaks) is approximately 1.8 box lengths which means the heart rate is approximately 166bpm. | The two ECG images shown above indicate the differences between a resting heart rate and heart rate during exercise (Adam Szulewski, n.d.). The image on the left is what a normal ECG would look like for a healthy person at rest. You can see that the distance between two QRS complexes (peaks) is about 3.4 box lengths. So, the heart rate for this person would be approximately 88bpm. The actual number calculated by the author for this ECG is 82bpm (Adam Szulewski, n.d.). So, this quick method of measuring heart rate is very useful as the estimate is relatively close to the actual calculated value. On the right is an image of what an ECG looks like for tachycardia which means fast heart. This is what a person’s ECG would look like when they are exercising. The distance between the two QRS complexes (peaks) is approximately 1.8 box lengths which means the heart rate is approximately 166bpm. | ||
| - | ====== References ====== | + | |
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| + | ====== How Exercise Prevents Different Cardiovascular Diseases ====== | ||
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| + | == Diabetes == | ||
| + | Exercise has both acute and chronic influences on patients with diabetes. Rapid changes in glucose concentration in blood occurs during and following an exercise. Type 2 diabetes are commonly comorbid with other cardiovascular diseases, and exercise can help with the improvement of insulin sensitivity as well as glucose disposal. Furthermore, exercise with diet can achieve weight loss, which can reduce the risk factor of diabetes (Chipkin et al., 2001). | ||
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| + | == Obesity == | ||
| + | Exercise is helpful in controlling obesity. Patients with BMI above 31 are considered obese, and regular exercise at an intensity of about 50% of their maximum heart rate, 5 times/week for about one hour/session (such as walking) has the potential to normalize weight body composition. Exercise can also reduce abdominal visceral fat, which is associated with impairments in carbohydrate and lipid metabolism. Exercise is helpful in controlling the energy intake and increases resting metabolic rate (Bouchard et al., 1993). | ||
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| + | ====== Conclusion and Future Implications ====== | ||
| + | In conclusion, exercise can improve a number of aspects of cognition and performance as well as prevention of cardiovascular disease such as coronary artery disease. Also, it can help control blood lipid abnormalities, diabetes and obesity. It would be important to come up with an effective exercise plan for patients with spinal cord injuries, the elderly or other conditions that may hinder an individual from practiing cardiovascular exercises. | ||
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| + | ====== Works Cited ====== | ||
| Atherosclerosis. (2018). National Heart, Lung and Blood Institute. Retrieved from https://www.nhlbi.nih.gov/health-topics/atherosclerosis | Atherosclerosis. (2018). National Heart, Lung and Blood Institute. Retrieved from https://www.nhlbi.nih.gov/health-topics/atherosclerosis | ||
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| Fletcher, G. F., Balady, G., Blair, S. N., Blumenthal, J., Caspersen, C., Chaitman, B., . . . Pollock, M. L. (1996). Statement on Exercise: Benefits and Recommendations for Physical Activity Programs for All Americans. Circulation,94(4), 857-862. doi:10.1161/01.cir.94.4.857 | Fletcher, G. F., Balady, G., Blair, S. N., Blumenthal, J., Caspersen, C., Chaitman, B., . . . Pollock, M. L. (1996). Statement on Exercise: Benefits and Recommendations for Physical Activity Programs for All Americans. Circulation,94(4), 857-862. doi:10.1161/01.cir.94.4.857 | ||
| + | Fu, Q., & Levine, B. D. (2013). Exercise and the autonomic nervous system. Handbook of Clinical Neurology, 117, 147–160. | ||
| + | https://doi.org/10.1016/B978-0-444-53491-0.00013-4 | ||
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| + | Gertz, K., Priller, J., Kronenberg, G., Fink, K. B., Winter, B., Schröck, H., ... & Dirnagl, U. (2006). Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase–dependent augmentation of neovascularization and cerebral blood flow. Circulation research, 99(10), 1132-1140. | ||
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| + | Gleeson, M., Bishop, N., Stensel, D.J., Lindley, M.R., Sarabjit, S., Nimmo, M.A. (2014). The Anti-Inflammatory Effects of Exercise: Mechanisms and Implications for the | ||
| + | Prevention of Common Diseases. Rheumatology, 53. Retrieved from http://www.nature.com/articles/nri3041 | ||
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| + | Golbidi, S., Laher, I. (2012). Exercise and the Cardiovascular System. Cardiol Res Pract. 2012, 210852. Retrieved from | ||
| + | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371347/ | ||
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| + | Gordon, N. F., Gulanick, M., Costa, F., Fletcher, G., Franklin, B. A., Roth, E. J., & Shephard, T. (2004). Physical activity and exercise recommendations for stroke survivors: | ||
| + | an American Heart Association scientific statement from the Council on Clinical Cardiology, Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention; | ||
| + | the Council on Cardiovascular Nursing; the Council on Nutrition, Physical Activity, and Metabolism; and the Stroke Council. Stroke, 35(5), 1230-1240. | ||
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| + | Joyner, M. J., & Green, D. J. (2009). Exercise protects the cardiovascular system: Effects beyond traditional risk factors. The Journal of Physiology, 587(23), 5551-5558. | ||
| + | doi:10.1113/jphysiol.2009.179432 | ||
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| + | Kim, M., Tomita, T., Kim, M., Sasai, H., Maeda, S., & Tanaka, K. (2009). Aerobic exercise training reduces epicardial fat in obese men. Journal of Applied Physiology, | ||
| + | 106(1), 5-11. Retrieved from | ||
| + | https://www.physiology.org/doi/abs/10.1152/japplphysiol.90756.2008?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed. | ||
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| + | Lee, B. A., & Oh, D. J. (2016). The effects of long-term aerobic exercise on cardiac structure, stroke volume of the left ventricle, and cardiac output. Journal of exercise | ||
| + | rehabilitation, 12(1), 37. | ||
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| + | The Heart Responds Differently to Exercise in Men vs. Women. (n.d.). Retrieved October 8, 2018, from http%3a%2f%2fwww.acc.org%2fabout-acc%2fpress-releases%2f2014%2f03%2f27%2f12%2f29%2fallison-peak-hr-pr | ||
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| + | Scott, G. Regulation of the heart [PDF document]. Retrieved from Lecture Notes Online Web site: | ||
| + | https://avenue.cllmcmaster.ca/d2l/le/content/229910/viewContent/1974510/View | ||
| + | Staff, H. (2012, March 6). Exercise Electrocardiogram. Retrieved October 31, 2018, from https://www.cardiosmart.org/Healthwise/hw23/4760/hw234760 | ||
| + | Szulewski, A. (n.d.). Analysis and Interpretation of the Electrocardiogram. Retrieved October 30, 2018, from https://meds.queensu.ca/central/assets/modules/ts-ecg/index.html | ||
| + | Zanesco, A., & Antunes, E. (2007). Effects of exercise training on the cardiovascular system: Pharmacological approaches. Pharmacology & Therapeutics,114(3), 307-317. doi:10.1016/j.pharmthera.2007.03.010 | ||
