Differences
This shows you the differences between two versions of the page.
| Both sides previous revision Previous revision Next revision | Previous revision | ||
|
group_1_presentation_2_-_attention_deficit_hyperactivity_disorder_adhd [2016/10/28 00:29] cunanajk |
group_1_presentation_2_-_attention_deficit_hyperactivity_disorder_adhd [2018/01/25 15:18] (current) |
||
|---|---|---|---|
| Line 285: | Line 285: | ||
| It was noted that dopamine levels were elevated in the nucleus accumbens as well (Bymaster et al., 2002). The nucleus accumbens is involved in the reward circuit, thereby increasing the susceptibility of abuse of psychostimulants; stimulants are considered a Schedule II drug meaning that there is a high potential for abuse (Allen et al., 2005). | It was noted that dopamine levels were elevated in the nucleus accumbens as well (Bymaster et al., 2002). The nucleus accumbens is involved in the reward circuit, thereby increasing the susceptibility of abuse of psychostimulants; stimulants are considered a Schedule II drug meaning that there is a high potential for abuse (Allen et al., 2005). | ||
| - | The downside is that some children reported to feel embarrassed at school when taking the medication and would often skip it (Tripp & Wickens, 2008). Another pitfall is that individuals with ADHD are often forgetful and may miss a dosage of their medication and thus impairs the efficacy of the drug (Tripp & Wickens, 2008). | + | The downside is that some children reported to feel embarrassed at school when taking the medication and would often skip it (Tripp & Wickens, 2008). |
| + | |||
| + | Another pitfall is that individuals with ADHD are often forgetful and may miss a dosage of their medication and thus impairs the efficacy of the drug (Tripp & Wickens, 2008). | ||
| In a specific study, the only side effects experienced were a dry mouth (Spencer et al., 2007). | In a specific study, the only side effects experienced were a dry mouth (Spencer et al., 2007). | ||
| Line 305: | Line 307: | ||
| ====Non stimulants==== | ====Non stimulants==== | ||
| Non stimulants are also prescribed to treat ADHD. An example is Atomoxetine, which has high selectivity for noradrenergic reuptake transporters and low selectivity for dopaminergic transporters in the nucleus accumbens, thereby increasing norepinephrine specifically in the prefrontal cortex (Allen et al., 2005). This is important because it does not disrupt sleep as severely; a side effect of stimulants (Allen et al., 2005). In addition, the low selectivity for dopamine means that the nucleus accumbens is not affected as severely as with stimulants, so there is less potential for abuse of this drug (Allen et al., 2005). | Non stimulants are also prescribed to treat ADHD. An example is Atomoxetine, which has high selectivity for noradrenergic reuptake transporters and low selectivity for dopaminergic transporters in the nucleus accumbens, thereby increasing norepinephrine specifically in the prefrontal cortex (Allen et al., 2005). This is important because it does not disrupt sleep as severely; a side effect of stimulants (Allen et al., 2005). In addition, the low selectivity for dopamine means that the nucleus accumbens is not affected as severely as with stimulants, so there is less potential for abuse of this drug (Allen et al., 2005). | ||
| + | |||
| + | ===== Conclusions and Future Implications ===== | ||
