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Optical Biopsy Theme
Description of the Technology
Optical Biopsy: to provide clinical information equivalent to that available from a physical biopsy. Usually assumed to mean equivalent to information available from stained sections of formalin fixed paraffin embedded biopsy tissue, specifically pathological assessment of same.
Basic modalities
Point Spectroscopy
Reflectance & Fluorescence Spatially Resolved Polarized Time Domain Raman IR
In Vivo Microscopic Imaging
Confocal Reflectance & Fluorescence Microscopy
Multi Photon Microscopy
Optical Coherence Tomography
Current research in the group
Haisha Zheng: Raman, Reflectance and Fluorescence Spectroscopy (Skin, Lung, GI)
Calum MacAulay: OCT, reflectance and fluorescence spectroscopy, In vivo confocal microendscopy (Lung, Oral, Cervix, GI)
Pierre Lane: OCT, reflectance and fluorescence spectroscopy, In vivo confocal microendscopy (Lung, Cervix, Ovarian)
Challenges
Significant clinical prblems
Key technology barriers
What the group can do
Commercialization pathways
potential industrial partners
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