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Optical Biopsy Theme

Description of the Technology

Optical Biopsy: to provide clinical information equivalent to that available from a physical biopsy. Usually assumed to mean equivalent to information available from stained sections of formalin fixed paraffin embedded biopsy tissue, specifically pathological assessment of same.

Basic modalities

Point Spectroscopy

Reflectance & Fluorescence
	Spatially Resolved
	Polarized
	Time Domain		
Raman
IR

In Vivo Microscopic Imaging

       Confocal Reflectance & Fluorescence Microscopy
       Multi Photon Microscopy
       Optical Coherence Tomography

Current research in the group

Haisha Zheng: Raman, Reflectance and Fluorescence Spectroscopy (Skin, Lung, GI)

Calum MacAulay: OCT, reflectance and fluorescence spectroscopy, In vivo confocal microendscopy (Lung, Oral, Cervix, GI)

Pierre Lane: OCT, reflectance and fluorescence spectroscopy, In vivo confocal microendscopy (Lung, Cervix, Ovarian)

Challenges

Significant clinical prblems

Key technology barriers

What the group can do

Commercialization pathways

potential industrial partners


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