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 ====== Case Study: Boy in the Bubble ======
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 David Vetter, often referred to as ‘the boy in the bubble’, was born with Severe Combined Immune Deficiency (SCID). Severe Combined Immune Deficiency is a potentially fatal primary immunodeficiency in which there is a combined absence of T-lymphocyte and B-lymphocyte function (Bosma, Custer, & Bosma, 1983). SCID is generally considered to be the most severe type of primary immunodeficiency disease and has the potential to cause extreme susceptibility to very serious infections. Affected infects are highly susceptible to recurring infections of bacteria, virus, and fungi and invariably die within 2 years of birth (Bosma G., Custer, & Bosma M., 1983).
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 ======References======
+Beck, G., & Habicht, G. S. (1996). Immunity and the Invertebrates. Retrieved from http://people.scs.carleton.ca/~soma/biosec/readings/sharkimmu-sciam-Nov1996.pdf
+Bosma, G. C., Custer, R. P., & Bosma, M. J. (1983). A severe combined immunodeficiency mutation in the mouse. Nature, 301(5900), 527.
+Boy in the bubble (1972). (n.d.). Retrieved from https://www.immunology.org/boy-in-the-bubble-1972
 Brain, M. (2019).  Different Roles- How Your Immune System Works.  Retrieved from https://health.howstuffworks.com/human-body/systems/immune/immune-system11.htm
@@ Line 133: / Line 141: @@
 Chaplin, D. D. (2010). Overview of the immune response. Journal of Allergy and Clinical Immunology, 125(2), S3-S23.
+Dinarello, C. A. (2000). Proinflammatory cytokines. Chest, 118(2), 503-508.
+Haberman, C. (2015, December 06). 'The Boy in the Bubble' Moved a World He Couldn't Touch. Retrieved from https://www.nytimes.com/2015/12/07/us/the-boy-in-the-bubble-moved-a-world-he-couldnt-touch.html
+Hoebe, K., Janssen, E., & Beutler, B. (2004). The interface between innate and adaptive immunity. Nature immunology, 5(10), 971.
+Immune Deficiency Foundation. (n.d.). Retrieved from https://primaryimmune.org/living-pi-explaining-pi-others/story-david
 Immuneresponse.org. (n.d).  Immune Response.  Retrieved from http://www.immuneresponse.org/
 Linnemeyer, P.A. (2008).  The Immune System- An Overview.  Retrieved from http://www.thebody.com/content/art1788.html
+Medzhitov, R., & Janeway Jr, C. (2000). Innate immunity. New England Journal of Medicine, 343(5), 338-344.
 National Institute of Allergy and Infectious Diseases. 2019.  Overview of the Immune System. Retrieved from https://www.niaid.nih.gov/research/immune-system-overview
 O'Byrne, K. J., & Dalgleish, A. G. (2001). Chronic immune activation and inflammation as the cause of malignancy. British journal of cancer, 85(4), 473.
-Beck, G., & Habicht, G. S. (1996). Immunity and the Invertebrates. Retrieved from http://people.scs.carleton.ca/~soma/biosec/readings/sharkimmu-sciam-Nov1996.pdf
 Olsen, L. (2018). The Future is Now for Immunology Research. Retrieved from
 https://www.rdmag.com/article/2018/05/future-now-immunology-research
-The Scientist. (2019). 24 Experts Forecast Future Trends In Immunology. Retrieved from
+Sakaguchi, S., Yamaguchi, T., Nomura, T., & Ono, M. (2008). Regulatory T cells and immune tolerance. Cell, 133(5), 775-787.
-https://www.the-scientist.com/research/24-experts-forecast-future-trends-in-immunology-62715
-Hoebe, K., Janssen, E., & Beutler, B. (2004). The interface between innate and adaptive immunity. Nature immunology, 5(10), 971.
+Sela-Culang, I., Kunik, V., & Ofran, Y. (2013). The structural basis of antibody-antigen recognition. Frontiers in immunology, 4, 302.
-Medzhitov, R., & Janeway Jr, C. (2000). Innate immunity. New England Journal of Medicine, 343(5), 338-344.
-Dinarello, C. A. (2000). Proinflammatory cytokines. Chest, 118(2), 503-508.
 Stossel, T. P. (1974). Phagocytosis. New England Journal of Medicine, 290(13), 717-723.
-Sela-Culang, I., Kunik, V., & Ofran, Y. (2013). The structural basis of antibody-antigen recognition. Frontiers in immunology, 4, 302.
+The Scientist. (2019). 24 Experts Forecast Future Trends In Immunology. Retrieved from
+https://www.the-scientist.com/research/24-experts-forecast-future-trends-in-immunology-62715
 Warrington, R., Watson, W., Kim, H. L., & Antonetti, F. R. (2011). An introduction to immunology and immunopathology. Allergy, Asthma & Clinical Immunology, 7(1), S1.
-Sakaguchi, S., Yamaguchi, T., Nomura, T., & Ono, M. (2008). Regulatory T cells and immune tolerance. Cell, 133(5), 775-787.
 Yamazaki, T., Akiba, H., Iwai, H., Matsuda, H., Aoki, M., Tanno, Y., ... & Azuma, M. (2002). Expression of programmed death 1 ligands by murine T cells and APC. The Journal of Immunology, 169(10), 5538-5545.
-Bosma, G. C., Custer, R. P., & Bosma, M. J. (1983). A severe combined immunodeficiency mutation in the mouse. Nature, 301(5900), 527.
-Boy in the bubble (1972). (n.d.). Retrieved from https://www.immunology.org/boy-in-the-bubble-1972
-Haberman, C. (2015, December 06). 'The Boy in the Bubble' Moved a World He Couldn't Touch. Retrieved from https://www.nytimes.com/2015/12/07/us/the-boy-in-the-bubble-moved-a-world-he-couldnt-touch.html
-Immune Deficiency Foundation. (n.d.). Retrieved from https://primaryimmune.org/living-pi-explaining-pi-others/story-david

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