Dr. Qiyin Fang 方淇音

Associate Professor of Engineering Physics
Canada Research Chair in Biophotonics
Department of Engineering Physics
School of Biomedical Engineering
Associate Member:
Department of Electrical & Computer Engineering &
Department of Medical Physics and Applied Radiation Sciences

B. S. Physics (Nankai)
M.S. Applied Physics (East Carolina University)
Ph.D. Biomedical Physics (East Carolina University)

Qiyin Fang (CV) is an associate professor of Engineering Physics at McMaster University and holds the Canada Research Chair in Biophotonics. He is a member of the McMaster School of Biomedical Engineering and associate member of the Department of Electrical and Computer Engineering. Dr. Fang's current research interests include steady-state and time-resolved fluorescence spectroscopy/imaging for biomedical applications, e.g. optical biopsy, wide-field imaging, endoscopy and microscopy.

Prior to his current position at McMaster, Dr. Fang was a research scientist in the Minimally Invasive Surgical Technology Institute at the Cedars-Sinai Medical Center in Los Angeles.

Dr. Fang obtained both of his graduate degrees from the East Carolina University, where he studied nanosecond laser pulse interaction with soft biological tissue both experimentally and theoretically. His undergraduate degree is from Nankai University, where he studied the light climbing effect in photorefractive Fe:LiNO3 crystals for holographic storage photonics devices.

Dr. Fang is a member of the International Society for Optical Engineering (SPIE), the Optical Society of American (OSA), and the Institute of Electrical and Electronics Engineers (IEEE).

2012

• Brent Emigh, Ran An, Eugene M. Hsu, Travis H. R. Crawford, Harold K. Haugen, Gregory R. Wohl, Joseph E. Hayward, and Qiyin Fang, “Porcine cortical bone ablation by ultrafast pulsed laser irradiation,” Journal of Biomedical Optics, 17(2):028001, 2012 (PDF)

• Anthony Tsikouras, Jin Ning, Sandy Ng, Rirchard Berman, David W. Andrews, and Qiyin Fang, “Streak camera crosstalk reduction using a multiple decay optical fiber bundle,” Optics Letters 37(2): 250-252, 2012. (PDF)

2011

• Regina Won Kay Leung, Shu-Chi Allison Yeh, and Qiyin Fang, “Effects of incomplete decay in fluorescence lifetime estimation,” Biomedical Optics Express 2(9):2517–2531, 2011. (PDF)

• Roy Chih Chung Wang, M. Jamal Deen, David Armstrong, and Qiyin Fang, “development of a catadioptric endoscope objective with forward and side views,” Journal of Biomedical Optics, 16(6):066015, 2011. (PDF)

• Munir El-Desouki, Darek Palubiak, M. Jamal Deen, Qiyin Fang, Ognian Marinov, “A novel, high-dynamic range, high-speed, and high sensitibility CMOS imager using time-domain single-photon counting and avalanche photodiodes,” IEEE Sensors Journal, 11(4): 1078-1083, 2011. (PDF)
  

• P. V. Butte, Q. Fang, J. A. Jo, W. H. Yong, B. K. Pikul, K. L. Black, and L. Marcu, Intraoperative delineation of primary brain tumors using time-resolved fluorescence spectroscopy,” Journal of Biomedical Optics, 15: 027008, 2010 (PDF)
  

2010

• J. F. Lo, P. Butte, Q. Fang, S. J. Chen, T. Papaioannou, E. S. Kim, M. Gundersen, L. Marcu, “Multilayered MOEMS tunable spectrometer for fluorescence lifetime detection,” IEEE Photonics Technology Letters, 20(7):486-488, 2010. (PDF)
  

2009

• Y. Yuan, J-Y. Hwang, M. Krishnamoorthy, J. Ning, Y. Zhang, K. Ye, R. C. Wang, M. J. Deen, Q. Fang, “A high throughput AOTF-based time-resolved fluorescence spectrometer for optical biopsy,” Optics Letters, 34(7): 1132-1134, 2009. (PDF)
  

• L. Marcu, J. A. Jo, Q. Fang, T. Papaioannou, T. Reil, J-H. Qiao, J. D. Baker, J. A. Freischlag, M. C. Fishbein, “Detection of Rupture-Prone Atherosclerotic Plaques by Time-Resolved Laser Induced Fluorescence Spectroscopy,” Atherosclerosis, Vol. 204(1): 156-164, 2009. (PDF)
  

• Joe Lo, Shi-Jui Chen, Qiyin Fang, Thanassis Papaioannou, Eun-Sok Kim, Martin Gundersen and Laura Marcu, “Performance of Diaphragmed Microlens for a Packaged Microspectrometer,” Sensors, 9: 859-868, 2009 (PDF)
  

• Munir El-Desouki, M. Jamal Deen, Qiyin Fang, Louis W. C. Liu, Frances Tse and David Armstrong, “CMOS Image Sensors for High Speed Applications,” Sensors, 9: 430-444, 2009. (PDF)
  

• N. Faramarzpour, M. M. El-Desouki, M. J. Deen, S. Shirani, Q. Fang, “CMOS photodetector systems for low-level light applications,” Journal of Material Sciences: Materials in Electronics, invited, 20(S1): 87-93, 2009. (PDF)
  

2008

• Ye Yuan, Thanassis Papaioannou, Qiyin Fang, “Single shot acquisition of time-resolved fluorescence spectra using a multiple delay optical fiber bundle,” Optics Letters, 33(8): 791-793, 2008. (PDF)
  

• N. Faramarzpour, M. J. Deen, S. Shirani and Q. Fang, “Fully Integrated Single Photon Avalanche Diode Detector in Standard CMOS 0.18μm Technology,” IEEE Transactions on Electron Devices, Vol. 55(3): 760-767, 2008. (PDF)
  

• J. A. Russell, K. R. Diamond, T. Collins, H. F. Tiedje, J. E. Hayward, T. J. Farrell, M. S. Patterson, Q. Fang, “Characterization of Fluorescence Lifetime of Photofrin and Delta-Aminolevulinic Acid Induced Protoporphyrin IX in Living Cells using Single and Two-photon Excitation,” IEEE Journal of Selected Topics in Quantum Electronics, 14(1): 158-166, 2008. (PDF)
  

• M. Kfouri, O. Marinov, P. Quevedo, N. Faramarzpour, S. Shirani, L. W-C. Liu, Q. Fang, M. J. Deen, “Towards a Miniaturized Wireless Fluorescence-Based Diagnostic Imaging System,” IEEE Journal of Se-lected Topics in Quantum Electronics, 14(1): 226-234, 2008. (PDF)
  

• N. Faramarzpour, M. M. El-Desouki, M. J. Deen, Q. Fang, S. Shrani and L. W-C. Liu, “CMOS Imaging for Biomedical Applications,” IEEE Potentials, May/June: 31-36, 2008. (PDF)
  

2007

• N. Faramarzpour, M. J. Deen, S. Shirani, Q. Fang, L. W. C. Liu, F. Campos, and J. W. Swart, “CMOS based active pixel for low-light-level detection: analysis and measurements,” IEEE Transactions on Elec-tron Devices, 54(12): 3229-3237, 2007. (PDF)
  

• J. A. Jo, L. Marcu, Q. Fang, T. Papaioannou, J. H. Qiao, M. C. Fishbein, B. Beseth, A. H. Dorafshar, T. Reil, D. Baker, J. Freischlag, “New Methods for Time-resolved Fluorescence Spectroscopy Data Analysis Based on the Laguerre Expansion Technique Applications in Tissue Diagnosis,” Methods of Information in Medicine, Vol. 46(2): 206-211, 2007. (PDF)
  

• J. F. Lo, Q. Fang, L. Marcu and E. S. Kim, “Wafer-level packaging of three-dimensional MOEMS device with lens diaphragm,” IEEE International Conference on Micro-Electrical-Mechanical Systems (MEMS), Jan. 21-25, 2007, Japan. (PDF)
  

2006

• J. A. Jo, Q. Fang, T. Papaioannou, J. D. Baker, A. H. Dorafshar, T. Reil, J. H. Qiao, M. C. Fishbein, J. A. Freischlag, L. Marcu; “Laguerre-based method for analysis of time-resolved fluorescence data: application to in-vivo characterization and diagnosis of atherosclerotic lesions,” Journal of Biomedical Optics, Vol. 11 (2): 021004, 2006 (PDF)

• W. H. Yong, P. V. Butte, B. K. Pikul, J. A. Jo, Q. Fang, T. Papaioannou, K. L. Black, and L. Marcu, “Distinction of brain tissue, low grade and high grade glioma with time-resolved fluorescence spectroscopy,” Frontiers in Biosciences, Vol. 11: 1255-1263, 2006. (PDF)

2005

• J. A. Jo, Q. Fang, L. Marcu, “Ultrafast method for the analysis of fluorescence lifetime imaging microscopy data based on the Laguerre expansion technique,” IEEE Journal of Selected Topics in Quantum Electronics, Vol. 11(4): 835-845, 2005. (PDF)

• L. Marcu, Q. Fang, J. A. Jo, T. Papaioannou, A. Dorafshar, T. Reil, J.H. Qiao, D. Baker, J. A. Freischlag M. C. Fishbein,. In-Vivo Detection of Macrophages in a Rabbit Atherosclerotic Model by Time-Resolved Laser-Induced Fluorescence Spectroscopy. Atherosclerosis, Vol. 181(2): 295-303, 2005. (PDF)

2004

• Q. Fang, T. Papaioannou, J. Jo, R. Vaitha, K. Shastry, and L. Marcu, “Time-domain laser-induced fluorescence spectroscopy apparatus for clinical diagnostics,” Review of Scientific Instrument, Vol. 75(1): 151-162, 2004. (PDF)

• Q. Fang and X. H. Hu, “Modeling of skin-tissue ablation by nanoseconds laser pulses from ultra violet to near-inferred and comparison with experimental results,” IEEE Journal of Quantum Electronics, Vol.40(1): 69-77, 2004. (PDF)

• J. A. Jo, Q. Fang, T. Papaioannou, and L. Marcu, “Fast model-free deconvolution of fluorescence decay for analysis of biological systems,” Journal of Biomedical Optics, Vol. 9(4):743-752, 2004. (PDF)

• T. Papaioannou, N. Preyer, Q. Fang, M. Carnohan, R. Ross, A. Brightwell, G. Cottone, L. Jones, and L. Marcu, “Effects of fiber-optic probe design and probe-to-target distance on diffuse reflectance measurements of turbid media: an experimental and computational study at 337 nm,” Applied Optics, Vol. 43(14): 2846-2860, 2004. (PDF)